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Science

The Protein Secretion Inhibition Platform is Kezar’s in-house drug discovery engine used to develop first-in-class small molecule therapeutics designed to block proteins implicated in a wide range of diseases. The protein secretion pathway is a universally functioning pathway to transport proteins out of the cell. By inhibiting select targets along this pathway, Kezar’s candidates have the potential to halt the secretion of disease-driving proteins responsible for perpetuating diseases spanning oncology, immuno-oncology and autoimmunity.